SmART+ Systems

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Image SmART, Plan SmART, Treat SmART

Mimicking clinical radiotherapy imaging and treatment workflows, the SmART+ systems deliver a highly sophisticated and expandable platform for advanced translational research. Designed for clinically relevant radiation experiments, this state-of-the-art small animal radiotherapy system combines intuitive software with multimodal imaging capabilities, including Cone-Beam CT, µCT, Bioluminescence (BLI), and optical imaging for precise, image guided radiation therapy applications.

 

Engineered for targeted irradiation for small animals, the SmART+ platform supports in vivo imaging and irradiation within a single integrated system, enabling highly accurate dose delivery and reproducible research outcomes. As a non radioactive animal irradiator and x ray alternative to cesium irradiator platforms, SmART+ provides a safer approach for modern preclinical radiation therapy system applications, from whole body irradiation small animal studies to advanced IGRT small animal workflows and translational radiotherapy research.

key Features
Rotational gantry, mimicking clinical radiotherapy imaging and treatment
Cone-Beam CT, µCT, and bioluminescent imaging modalities
Fully integrated treatment planning and delivery software with multi-modality image guidance
Dynamic collimator and X-Y-Z animal stage delivers precise and accurate focal irradiation
Designed to image, target and irradiate specimens, up to the size of a NZ rabbit
Expand translational radiation research with OptiFLEX imaging. Discover new insights through Fluorescence, Bioluminescence, and Chemiluminescence
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Application Highlights
Stem Cell Research
Cancer Research
Immunotherapy
Radiation injury studies
Translational Radiobiology
Chemoradiotherapy
Normal Tissue Toxicity
Imaging and Biomarkers

With its rapidly advancing imaging and planning capabilities, the SmART system allows the user – whether they are a molecular biologist or an imaging physicist – to truly pave the way for cutting-edge translational radiobiology applications.

Kiran Beera
Product Manager, Precision X-Ray
See what the experts are doing

The Local Microenvironment Suppresses the Synergy Between Irradiation and Anti-PD1 Therapy in Breast-to-Brain Metastasis

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Bioluminescence (BLI) & Chemiluminescence Imaging using Irradiators

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Elective nodal irradiation mitigates local and systemic immunity generated by combination radiation and immunotherapy in head and neck tumors

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Effects of the depletion of neural progenitors by focal X-ray irradiation on song production and perception in canaries

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FAQs

The SmART+ platform is built for precision preclinical research, focusing specifically on translational research with its ability to mimic clinical environments. Study areas include radiation oncology, radiation biology, neo-adjuvant drug discovery, and more.

Yes — select SmART+ configurations offer dual-mode capability, allowing users to switch between conventional and FLASH techniques with ease on the same platform.

The SmART+ systems integrate high-resolution cone-beam CT imaging and motorized 3D positioning for image-guided irradiation accuracy within sub-millimeter precision. Options include even higher resolution microCT for visualizing bone and internal organ structure and the OPTIFLEX module that integrates fluorescence, bioluminescence, and chemiluminescence imaging.

All systems comply with FDA, CE, and IEC radiation safety standards, and include fully interlocked shielding for operator protection.

The SmART+ supports a variety of preclinical models, from small animals to tissue phantoms, with adjustable platforms and customizable sample holders for diverse study designs.

Contact Us

14 New Road
Madison, CT, 06443

phone:
203.484.2011
fax:
203.484.2012